Associate Professor

Faculty Details

  • Citations 386
  • HIndex 11
  • i10 Index 13
  • Mobile 9419018174
  • Email shajrulamin@uok.edu.in shajrul@rediffmail.com
  • Administrative position Held Head, Department of Biochemistry; Coordinator, Clinical Biochemistry



Research Papers Published

  • "Oxidative stress mediated Ca2+ release manifests endoplasmic reticulum stress leading to unfolded protein response in UV-B irradiated human skin cells." Journal of Dermatol Sci., 75(1): 24 -35 {ISSN: 0923-1811} Impact Factor= 3.71
  • "A critically endangered medicinal plant of Kashmir Valley." Oxidative Medicine and Cellular Longevity, 2014(2014): 1 -8 {ISSN: 1942-0900} Impact Factor= 3.393
  • "Antioxidant and hepatoprotective effects of Cratagus songerica methanol extract." Journal of Environmental Pathology Toxicology and Oncology, 33(2): 131 -142 {ISSN: 0731-8898} Impact Factor= 1.107
  • "Association between GSTM1 and GSTT1 polymorphisms and esophageal squamous cell carcinoma, results from a case-control study in Kashmir, India" Tumor Biol., 2014(2014): 1 -7 {ISSN: 1010-4283} Impact Factor= 2.84
  • "TCF4 may act as a tumour suppressor gene in colorectal carcinogenesis." World Journal of Pharmaceutical Research., 3(8): 1 -13 {ISSN: 2277-7105} Impact Factor= 5.045
  • "Plant - derived protease inhibitors LC-pi (Lavatera Cashmeriana) inhibit human lung cancer cell proliferation in vitro." Nutr Cancer, 67(1): 156 - {ISSN: ISSN: 0163} Impact Factor= 2.32
  • "Association between GSTM1 and GSTT1 polymorphisms and esophageal squamous cell carcinoma: results from a case-control study in Kashmir, India." Tumor Biol., 36(4): 2613 -2619 {ISSN: : 1010-428} Impact Factor= 3.62
  • "Inflammation: A multidimensional insight with advanced focus on natural anti-inflammatory therapeutic compounds" Current Medicinal Chemistry, 23(33): 3775 -3800 {ISSN: 0929-8673} Impact Factor= 3.45
  • "A comprehensive review on the phytochemical and pharmacological aspects of Podophyllum hexandrum: a high value medicinal plant." Adv. Biomed. Pharma, 3(4): 216 -226 {ISSN: 2313-7479} Impact Factor= 0.435
  • "Type 2 diabetes and metabolic syndrome – adipokine levels and effect of drugs." Gynecological Endocrinology, 1(4): DOI No. 10.1080/09513590.2016.1207165 {ISSN: 0951-3590} Impact Factor= 1.413
  • "Efficacy of Aqueous and Methanolic Extracts of Rheum Spiciformis against Pathogenic Bacterial and Fungal Strains." Journal of Clinical and Diagnostic Research, 10(9): 18 -22 {ISSN: 0973-709} Impact Factor= 0.3
  • "Evaluation of antimicrobial and antioxidant a ctivities of Swertia petiolata" Adv. Biomed. Pharma., 3(5): 272 -279 {ISSN: 2313-7479} Impact Factor= 0.435
  • "Type 2 diabetes and metabolic syndrome – adipokine levels and effect of drugs" Gynecological Endocrinology, 33(1): 75 -78 {ISSN: 0951-359} Impact Factor= 1.413
  • "Evaluation of Antibacterial, Antifungal and Phytochemical Screening of Solanum nigrum." Biochemistry and Analytical Biochemistry, 6(1): 309 -320 {ISSN: 2161-1009}
  • "Comparative analysis of clinical, biochemical and hormonal profile of obese versus lean Kashmiri PCOS patients –A pilot study" International Journal of Advances in Science Engineering and Technology, 5(2): 55 -60 {ISSN: 2321-9009}
  • "Metabolic Derangements and Possible CVD Risk in PCOS Women Owing to Use of OCP’s as a Treatment Mode – Pros and Cons" J Endocrinol Diabetes Obes, 5(3): 1101 -1119 {ISSN: 2333-6692}
  • "Design and synthesis of indolopyridone hybrids as new antituberculosis agents." Microbial Pathogenesis, 113(1): 330 -334 {ISSN: 0882-4010} Impact Factor= 2.009
  • "The Lys469glu/K469E Polymorphism of the Inflammatory Gene Intercellular Adhesion Molecule-1 Lacks any Apparent Role in the Polycystic Ovary Syndrome in Kashmiri Women: A Case Control Study" Asian Pacific journal of cancer prevention, 18(11): 2925 -2930 {ISSN: 2222-1808} Impact Factor= 2.5
  • "Synthesis, Biological Evaluation and Structure - Activity Relationship of 2-Phenylaminomethylene-cyclohexane-1,3-diones as Specific Anti-tuberculosis Agents" Med. Chem. Commun, 8(11): 2133 -2141 Impact Factor= 2.608
  • "Polycystic ovary syndrome (pcos) and related diseases." Precision Medicine, 2(1): 23 -29 {ISSN: 2456-2254}
  • "In vitro antimycobacterial activity of 2-(((2-hydroxyphenyl)amino)methylene)-5,5-dimethylcyclohexane-1,3-dione: A new chemical entity against Mycobacterium tuberculosis" International Journal of Antimicrobial Agents, 52(2): 265 -268 {ISSN: 0924-8579} Impact Factor= 4.307
  • "XRCC1 Arg194Trp polymorphism is no risk factor for skin cancer development in Kashmiri population" Egyptian Journal of Medical Human Genetics, 19(2): 91 -95 {ISSN: 1110-8630} Impact Factor= 0.53
  • "Scenario of hypothyroidism and its recent advances in the diagnosis and management – a review" International Journal of Recent Scientific Research, 9(3): 25288 -25299 {ISSN: 0976-3031}
  • "Physico-chemical Characterization and Anti-microbial Activity of Serine Protease Inhibitors Purified from the seeds of Sophora japonica" Pakistan Journal of Biological Sciences, 21(9): 432 -440 {ISSN: 1028-8880} Impact Factor= 0.38
  • "Therapeutic Strategies and Protein-Protein Interactions in Cancer: Mechanistic View" Current Cancer Drug Targets, 18(1): 1 -19 {ISSN: 1389-4501} Impact Factor= 3.11
  • "Impact of catechol-O-methyltransferase gene variants on methylation status of P16 and MGMT genes and their down regulation in colorectal cancer" European Journal of Cancer Prevention, 28(2): DOI No. 10.1097/CEJ.0000000000000485 {ISSN: 0959-8278} Impact Factor= 2.886
  • "Association of adiponectin gene polymorphism with Type 2 diabetes and metabolic syndrome" Translational Metabolic Syndrome Research, 1(1): 39 -47 {ISSN: 2588-9303}
  • "Effect of Paraoxonase 1 (PON1) gene polymorphism on PON1 activity, HDL, LDL and MDA levels in women with Polycystic Ovary Syndrome (PCOS): a case control study" Meta Gene, 20(1): DOI No. doi.org/10.1016/J.mgene.2019.1 {ISSN: 2214-5400} Impact Factor= 0.88
  • "Evaluation of antioxidant defense markers in relation to hormonal and insulin parameters in women with polycystic ovary syndrome (PCOS): A case-control study" Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13(3): 1957 -1961 {ISSN: 1871-4021} Impact Factor= 0.961
  • "Elevated fasting insulin is associated with cardiovascular and metabolic risk in women with polycystic ovary syndrome" Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13(3): 2098 -2105 {ISSN: 1871-4021} Impact Factor= 0.961
  • "Oral contraceptive use increases risk of inflammatory and coagulatory disorders in women with Polycystic Ovarian Syndrome: An observational study" Scientific Reports, 9(1): DOI No. https://doi.org/10.1038/s41598 Impact Factor= 4.1
  • "Hyperandrogenism in polycystic ovarian syndrome and role of CYP genes: a review" Egyptian Journal of Medical Human Genetics, 20(25): 1 -20
  • "Exploring proteomic drug targets, therapeutic strategies and protein-protein interactions in cancer: mechanistic view" Current cancer drug targets, 19(6): 430 -448 {ISSN: 15680096} Impact Factor= 3.52
  • "Insulin gene VNTR class III allele is a risk factor for insulin resistance in Kashmiri women with polycystic ovary syndrome" Meta Gene, 21(2019): DOI No. https://doi.org/10.1016/j.mgen {ISSN: 2214-5400} Impact Factor= 0.88

Books Published

  • "Protein Misfolding: In perspective of loss and gain of function. Proteostasis and Chaperone Surveillance.". Speringer. {ISBN: 978-81-322-2466-2} pp 24
  • "Handbook of Lipid metabolism". Book Enclave Publishers F-11, s.s. Tower, Dhameni Street, Jaipur-302003. {ISBN: 978-81-8152-462-1} pp 120
  • "Clinical Perspectives of Posttranslational Modifications. Protein Modificomics". Elsevier. {ISBN: 978-0-12-811913-6} pp 34

Research Projects Details:

Title of the ProjectFunding AgencyDatedAmount (in Rs.)
Insulin gene VNTR polymorphism in Kashmiri women with polycystic ovary syndromeICMR01-03-20151,850,000.00
Expression analysis and polymorphism of CYP11, CYP17 and CYP19 gene and their relationship with hyperandrogenism and PCOS in Kashmiri womenDHR, Ministry of Health and Family Welfare, Government of India, New Delhi15-07-20172,966,080.00
Expression analysis and polymorphism of CYP11, CYP17 and CYP19 gene and their relationship with hyperandrogenism and PCOS in Kashmiri womenDepartment of Health Research, Ministry of Health and Family Welfare, Government of India, New Delhi15-07-20172,966,080.00

Research Scholars:

NameCourseStatusNature
Rabiya MajeedM.Phil Awarded Whole Time
Khalid Bashir DarM.Phil Awarded Whole Time
Sairish AshrafM.Phil Awarded Whole Time
Rouf MaqboolM.Phil Awarded Whole Time
Syed Sakina MustafaM.Phil Awarded Whole Time
Qudsia FatimaM.Phil Awarded Whole Time
Mudasir NabiM.Phil Awarded Whole Time
Muzafar Ahmad RatherM.Phil Awarded Whole Time
Younus Ahmad BhatM.Phil Awarded Whole Time
Hilal ahmd WaniPh.D Awarded Whole Time
Syed RakhashandaPh.D Awarded Whole Time
Farukh RanaPh.D Awarded Whole Time
Rabia Farooq JanPh.D Awarded Whole Time
Muzaffar Ahmad RatherPh.D Awarded Whole Time

Teaching:

DepartmentSubjectCourse TaughtSemester
Bio-ChemistryMSc BiochemistryPlant Biochemistry1
Bio-ChemistryMSc Biochemistry (June 2019)Enzymology2
Bio-ChemistryMSc BiochemistryMicronutrition4