Biochemistry

School of Biological Sciences

Research Papers Published

• "Oxidative stress mediated Ca2+ release manifests endoplasmic reticulum stress leading to unfolded protein response in UV-B irradiated human skin cells." Journal of Dermatol Sci., 75(1): 24 -35 {ISSN: 0923-1811} Impact Factor= 3.71
• "A critically endangered medicinal plant of Kashmir Valley." Oxidative Medicine and Cellular Longevity, 2014(2014): 1 -8 {ISSN: 1942-0900} Impact Factor= 3.393
• "Antioxidant and hepatoprotective effects of Cratagus songerica methanol extract." Journal of Environmental Pathology Toxicology and Oncology, 33(2): 131 -142 {ISSN: 0731-8898} Impact Factor= 1.107
• "Association between GSTM1 and GSTT1 polymorphisms and esophageal squamous cell carcinoma, results from a case-control study in Kashmir, India" Tumor Biol., 2014(2014): 1 -7 {ISSN: 1010-4283} Impact Factor= 2.84
• "TCF4 may act as a tumour suppressor gene in colorectal carcinogenesis." World Journal of Pharmaceutical Research., 3(8): 1 -13 {ISSN: 2277-7105} Impact Factor= 5.045
• "Plant - derived protease inhibitors LC-pi (Lavatera Cashmeriana) inhibit human lung cancer cell proliferation in vitro." Nutr Cancer, 67(1): 156 - {ISSN: ISSN: 0163} Impact Factor= 2.32
• "Association between GSTM1 and GSTT1 polymorphisms and esophageal squamous cell carcinoma: results from a case-control study in Kashmir, India." Tumor Biol., 36(4): 2613 -2619 {ISSN: : 1010-428} Impact Factor= 3.62
• "Inflammation: A multidimensional insight with advanced focus on natural anti-inflammatory therapeutic compounds" Current Medicinal Chemistry, 23(33): 3775 -3800 {ISSN: 0929-8673} Impact Factor= 3.45
• "A comprehensive review on the phytochemical and pharmacological aspects of Podophyllum hexandrum: a high value medicinal plant." Adv. Biomed. Pharma, 3(4): 216 -226 {ISSN: 2313-7479} Impact Factor= 0.435
• "Type 2 diabetes and metabolic syndrome – adipokine levels and effect of drugs." Gynecological Endocrinology, 1(4): DOI No. 10.1080/09513590.2016.1207165 {ISSN: 0951-3590} Impact Factor= 1.413
• "Efficacy of Aqueous and Methanolic Extracts of Rheum Spiciformis against Pathogenic Bacterial and Fungal Strains." Journal of Clinical and Diagnostic Research, 10(9): 18 -22 {ISSN: 0973-709} Impact Factor= 0.3
• "Evaluation of antimicrobial and antioxidant a ctivities of Swertia petiolata" Adv. Biomed. Pharma., 3(5): 272 -279 {ISSN: 2313-7479} Impact Factor= 0.435
• "Type 2 diabetes and metabolic syndrome – adipokine levels and effect of drugs" Gynecological Endocrinology, 33(1): 75 -78 {ISSN: 0951-359} Impact Factor= 1.413
• "Evaluation of Antibacterial, Antifungal and Phytochemical Screening of Solanum nigrum." Biochemistry and Analytical Biochemistry, 6(1): 309 -320 {ISSN: 2161-1009} Impact Factor=
• "Comparative analysis of clinical, biochemical and hormonal profile of obese versus lean Kashmiri PCOS patients –A pilot study" International Journal of Advances in Science Engineering and Technology, 5(2): 55 -60 {ISSN: 2321-9009} Impact Factor=
• "Metabolic Derangements and Possible CVD Risk in PCOS Women Owing to Use of OCP’s as a Treatment Mode – Pros and Cons" J Endocrinol Diabetes Obes, 5(3): 1101 -1119 {ISSN: 2333-6692} Impact Factor=
• "Design and synthesis of indolopyridone hybrids as new antituberculosis agents." Microbial Pathogenesis, 113(1): 330 -334 {ISSN: 0882-4010} Impact Factor= 2.009
• "The Lys469glu/K469E Polymorphism of the Inflammatory Gene Intercellular Adhesion Molecule-1 Lacks any Apparent Role in the Polycystic Ovary Syndrome in Kashmiri Women: A Case Control Study" Asian Pacific journal of cancer prevention, 18(11): 2925 -2930 {ISSN: 2222-1808} Impact Factor= 2.5
• "Synthesis, Biological Evaluation and Structure - Activity Relationship of 2-Phenylaminomethylene-cyclohexane-1,3-diones as Specific Anti-tuberculosis Agents" Med. Chem. Commun, 8(11): 2133 -2141 Impact Factor= 2.608
• "Polycystic ovary syndrome (pcos) and related diseases." Precision Medicine, 2(1): 23 -29 {ISSN: 2456-2254} Impact Factor=
• "In vitro antimycobacterial activity of 2-(((2-hydroxyphenyl)amino)methylene)-5,5-dimethylcyclohexane-1,3-dione: A new chemical entity against Mycobacterium tuberculosis" International Journal of Antimicrobial Agents, 52(2): 265 -268 {ISSN: 0924-8579} Impact Factor= 4.307
• "XRCC1 Arg194Trp polymorphism is no risk factor for skin cancer development in Kashmiri population" Egyptian Journal of Medical Human Genetics, 19(2): 91 -95 {ISSN: 1110-8630} Impact Factor= 0.53
• "Scenario of hypothyroidism and its recent advances in the diagnosis and management – a review" International Journal of Recent Scientific Research, 9(3): 25288 -25299 {ISSN: 0976-3031} Impact Factor=
• "Physico-chemical Characterization and Anti-microbial Activity of Serine Protease Inhibitors Purified from the seeds of Sophora japonica" Pakistan Journal of Biological Sciences, 21(9): 432 -440 {ISSN: 1028-8880} Impact Factor= 0.38
• "Therapeutic Strategies and Protein-Protein Interactions in Cancer: Mechanistic View" Current Cancer Drug Targets, 18(1): 1 -19 {ISSN: 1389-4501} Impact Factor= 3.11
• "Impact of catechol-O-methyltransferase gene variants on methylation status of P16 and MGMT genes and their down regulation in colorectal cancer" European Journal of Cancer Prevention, 28(2): DOI No. 10.1097/CEJ.0000000000000485 {ISSN: 0959-8278} Impact Factor= 2.886
• "Association of adiponectin gene polymorphism with Type 2 diabetes and metabolic syndrome" Translational Metabolic Syndrome Research, 1(1): 39 -47 {ISSN: 2588-9303} Impact Factor=
• "Effect of Paraoxonase 1 (PON1) gene polymorphism on PON1 activity, HDL, LDL and MDA levels in women with Polycystic Ovary Syndrome (PCOS): a case control study" Meta Gene, 20(1): DOI No. doi.org/10.1016/J.mgene.2019.1 {ISSN: 2214-5400} Impact Factor= 0.88
• "Evaluation of antioxidant defense markers in relation to hormonal and insulin parameters in women with polycystic ovary syndrome (PCOS): A case-control study" Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13(3): 1957 -1961 {ISSN: 1871-4021} Impact Factor= 0.961
• "Elevated fasting insulin is associated with cardiovascular and metabolic risk in women with polycystic ovary syndrome" Diabetes & Metabolic Syndrome: Clinical Research & Reviews, 13(3): 2098 -2105 {ISSN: 1871-4021} Impact Factor= 0.961
• "Oral contraceptive use increases risk of inflammatory and coagulatory disorders in women with Polycystic Ovarian Syndrome: An observational study" Scientific Reports, 9(1): DOI No. https://doi.org/10.1038/s41598 Impact Factor= 4.1
• "Hyperandrogenism in polycystic ovarian syndrome and role of CYP genes: a review" Egyptian Journal of Medical Human Genetics, 20(25): 1 -20 Impact Factor=
• "Exploring proteomic drug targets, therapeutic strategies and protein-protein interactions in cancer: mechanistic view" Current cancer drug targets, 19(6): 430 -448 {ISSN: 15680096} Impact Factor= 3.52
• "Insulin gene VNTR class III allele is a risk factor for insulin resistance in Kashmiri women with polycystic ovary syndrome" Meta Gene, 21(2019): DOI No. https://doi.org/10.1016/j.mgen {ISSN: 2214-5400} Impact Factor= 0.88
• "CYP17 gene polymorphic sequence variation is associated with hyperandrogenism in Kashmiri women with polycystic ovarian syndrome" Gynecological Endocrinology, 1(1): DOI No. https://doi.org/10.1080/09513 {ISSN: 09513590} Impact Factor= 1.35
• "Active Cousinia thomsonii Extracts Modulate Expression of Crucial Proinflammatory Mediators/Cytokines and NF?B Cascade in Lipopolysaccharide-Induced Albino" Journal of Inflammation Research, 13(3): 829 -845 {ISSN: 1178-7031} Impact Factor= 4.95
• "Elucidating critical proteinopathic mechanisms and potential drug targets in neurodegeneration" Cellular and molecular neurobiology, 40(3): 313 -345 {ISSN: 0272-4340} Impact Factor= 3.6
• "Impact of rs2414096 polymorphism of CYP19 gene on susceptibility of polycystic ovary syndrome and hyperandrogenism in Kashmiri women." Scientific Reports, 11(1): DOI No. 10.1038/s41598-021-92265-1 {ISSN: 2045-2322} Impact Factor= 4.379
• "Androgen Receptor Coregulator Long Non Coding RNA CTBP1-AS Is Associated With Polycystic Ovary Syndrome in Kashmiri Women. Endocrine Doi: 10.1007/s12020-021-02894-9 ISSN:" Endocrine, 2021(1): DOI No. 10.1007/s12020-021-02894-9 {ISSN: 1355-008X} Impact Factor= 3.63
• "Clinical Manifestations of Hyperandrogenism and Ovulatory Dysfunction are not associated with His1058 C/T SNP(rs1799817) polymorphism of Insulin Receptor Gene Tyrosine Kinase Domain in Kashmiri Women with PCOS" International Journal of Endocrinology, 2021(1): DOI No. 10.1155/2021/7522487 {ISSN: 1687-8337} Impact Factor= 3.25
• "Insulin receptor substrate1 Gly972Arg (rs1801278) polymorphism is associated with obesity and insulin resistance in Kashmiri women with polycystic ovary syndrome" Genes, 13(1): DOI No. 10.3390/genes/3081463 {ISSN: 2073-4425} Impact Factor= 4.09

Books Published

• "Protein Misfolding: In perspective of loss and gain of function. Proteostasis and Chaperone Surveillance.". Speringer. {ISBN: 978-81-322-2466-2} pp 24
• "Handbook of Lipid metabolism". Book Enclave Publishers F-11, s.s. Tower, Dhameni Street, Jaipur-302003. {ISBN: 978-81-8152-462-1} pp 120
• "Clinical Perspectives of Posttranslational Modifications. Protein Modificomics". Elsevier. {ISBN: 978-0-12-811913-6} pp 34
• "Long non-coding RNAs in neurological diseases: A mechanical insight". Cambridge Scholars Publishing. {ISBN: 1-5275-5821-5} pp 24
• "Long non-coding RNAs in Hormonal disorders with a focus on polycystic ovary syndrome". Cambridge Scholars Publishing. {ISBN: 1-5275-5821-5} pp 19
• "Oxidative stress and antioxidants: From free radicals to disease pathogenesis". Scholars Press, Beau Bassin Mauritius. {ISBN: 978-613-8-94042-5} pp 120

Research Projects Details:

Research Scholars:

Teaching: